Dexmedetomidine Hydrochloride Meeting CP & EP Standards

Having established close cooperative relations with many pharmaceutical companies, universities, and research institutions, Alfa Chemistry decided to enlarge its active pharmaceutical ingredient (API) supply continuously in the hope of providing a more diversified product portfolio for customers. Fairly recently, the company announced the launch of dexmedetomidine hydrochloride, another API demanded in large quantities for both pharmaceutical preparation and scientific research.


Dexmedetomidine hydrochloride is the salt form of dexmedetomidine, an imidazole derivative and active d-isomer of medetomidine consisting of analgesic, anxiolytic, and sedative activities.


In order to make surgeries safer, more comfortable, and painless for patients, many hospitals are willing to introduce dexmedetomidine hydrochloride to improve the sufficiency of anaesthesia. Overall, dexmedetomidine hydrochloride can be used for general anaesthesia, local anaesthesia, spinal anaesthesia, and nerve-blocking anaesthesia in clinical operations. The Marketing Chief of Alfa Chemistry said: “As a chemical supplier, we are specialized in providing dexmedetomidine hydrochloride as raw APIs for researchers across the globe.”


In the science community, more application possibilities have been explored with the increase in studies carried out regarding dexmedetomidine hydrochloride. Currently, some researchers have focused on the effects of dexmedetomidine pretreatment on lipopolysaccharide-induced acute lung injury in mice, while others have focused on the impact of primary neonatal rat cardiomyocytes under hypoxic/reoxygenation conditions using dexmedetomidine hydrochloride.


Compared with benzodiazepines and propofol, the incidences of delirium and coma associated with dexmedetomidine are relatively lower. Therefore, dexmedetomidine gradually becomes an alternative to benzodiazepines and propofol in sedation. Still, more studies regarding the efficacy and safety of dexmedetomidine hydrochloride are needed.


“We believe our synthetic dexmedetomidine hydrochloride is quality enough to aid all research-related applications and serve as API raw materials for industrial manufacturing. With a strong technical platform and professional technicians, we can ensure the safety of API production in line with the quality standards and the continuous improvement of cGMP requirements,” the Marketing Chief further added.


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About Alfa Chemistry

Having more than 20 years of experience in the API field, Alfa Chemistry never forgets its mission and constantly provides innovative small molecule APIs for researchers as well as global pharmaceutical companies. With a balanced and expanding product portfolio combined with expertise, the technical team of Alfa Chemistry is also capable of providing attractive solutions for drug developers. As for now, Alfa Chemistry offers the following synthetic chemical APIs: Epalrestat, Edaravone, Donepezil, Dexmedetomidine Hydrochloride, Lenalidomide, Parecoxib Sodium, Rivaroxaban, Tofacitinib Citrate, and Tamoxifen Citrate.

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