Nucleic acid amplification testing (NAAT), which looks for specific viral DNA sequences using real-time or conventional polymerase chain reactions (PCR), is used to confirm MPXV infection. Sequencing can be done alone or in conjunction with PCR. The first PCR reaction finds OPXV, but it cannot tell what species it is. A second step can then be taken to precisely detect MPXV, which may be PCR-based or involve sequencing. Creative Biolabs has been keeping a close eye on the development of the epidemic situation and accelerating the development of PCR primers and monkeypox probes.