Unraveling Cancer Evolution

Next-generation sequencing technologies are always evolving, and this has allowed gene sequencing to reach the level of individual cells. Malignant tumors are known to be a molecular illness, and a key factor in their formation is the inactivation of tumor suppressor genes and the activation of oncogenes based on variations in gene levels. Additionally, one tumor or a group of tumors may contain varying numbers and varieties of tumor cells. Thus, an in-depth analysis of malignant tumors using single-cell sequencing technology can uncover the diversity that contributes to the genesis and evolution of malignant tumors, aiding in our understanding of the growth and evolution of tumors at the individual level.

For more: single cell omics for TILs

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